For nuclear power plant design and operation, introductory comments on nuclear materials, radiation effects, corrosion damage, and nuclear fuels are included in this course. Introduction remarks on radiations, simple calculation on gamma ray and neutron shielding. Radiation effects, units and calculational methods are described basically. Various sources of radiation and standards of various radiation effects are explained. Also quantitative effects of radiation on human and corresponding radiation effects are calculated and analyzed. Reactor licensing, safety principles and dispersions of effluents from nuclear facilities are discussed. Finally reactor incidents, accidents and risk analysis are briefly introduced.